Close Menu
  • Home
  • News
    • Local
  • Opinion
  • Business
  • Health
  • Education
  • Sports
  • Podcast

Subscribe to Updates

Get the latest creative news from FooBar about art, design and business.

What's Hot

Trust in Mainstream Media at a New Low, But the Black Press Stands as the Trusted Voice

Pew Finds Just 6% of Journalists Are Black as Crisis Grows with Recent Firings

Republicans Shutdown Government

Facebook X (Twitter) Instagram
  • Lifestyle
  • Podcast
  • Contact Us
Facebook X (Twitter) Instagram Pinterest Vimeo
The Windy City Word
  • Home
  • News
    1. Local
    2. View All

    Youth curfew vote stalled in Chicago City Council’s public safety committee

    Organizers, CBA Coalition pushback on proposed luxury hotel near Obama Presidential Center

    New petition calls for state oversight and new leadership at Roseland Community Hospital

    UFC Gym to replace shuttered Esporta in Morgan Park

    Unbreakable: Black Women and Mental Health

    A Question of a Government Shutdown?

    Jackson State Dominates Southern on the Road, Wins Boombox Classic

    Conference Commissioners Discuss Name, Image, and Likeness in Washington

  • Opinion

    Capitalize on Slower Car Dealership Sales in 2025

    The High Cost Of Wealth Worship

    What Every Black Child Needs in the World

    Changing the Game: Westside Mom Shares Bally’s Job Experience with Son

    The Subtle Signs of Emotional Abuse: 10 Common Patterns

  • Business

    Illinois Department of Innovation & Technology supplier diversity office to host procurement webinar for vendors

    Crusader Publisher host Ukrainian Tech Businessmen eyeing Gary investment

    Sims applauds $220,000 in local Back to Business grants

    New Hire360 partnership to support diversity in local trades

    Taking your small business to the next level

  • Health

    Unbreakable: Black Women and Mental Health

    A Question of a Government Shutdown?

    Democrats Dig In: Healthcare at the Center of Looming Shutdown Fight

    Democrats Dig In: Healthcare at the Center of Looming Shutdown Fight

    COMMENTARY: Health Care is a Civil Rights Issue

  • Education

    Alabama’s CHOOSE Act: A Promise and a Responsibility

    After Plunge, Black Students Enroll in Harvard

    What Is Montessori Education?

    Nation’s Report Card Shows Drop in Reading, Math, and Science Scores

    The Lasting Impact of Bedtime Stories

  • Sports

    Jackson State Dominates Southern on the Road, Wins Boombox Classic

    Conference Commissioners Discuss Name, Image, and Likeness in Washington

    Week 4 HBCU Football Recap: DeSean Jackson’s Delaware State Wins Big

    Turning the Tide: Unity, History, and the Future of College Football in Mississippi

    Week Three HBCU Football Recap: Grambling Cornerback Tyrell Raby Continues to Shine

  • Podcast
The Windy City Word
Health

Researchers say Silent brain changes precede Alzheimer’s

StaffBy StaffNo Comments3 Mins Read
Facebook Twitter Pinterest Telegram LinkedIn Tumblr Email Reddit
A closeup of a human brain affected by Alzheimer’s disease, is displayed at the Museum of Neuroanatomy at the University at Buffalo in Buffalo, N.Y., on Oct. 7, 2003. According to findings published Wednesday, Feb. 21, 2024 in the New England Journal of Medicine, Alzheimer’s quietly ravages the brain long before symptoms appear and now scientists are getting a closer look at the domino-like sequence of those changes _ a potential window to one day intervene.
Share
Facebook Twitter LinkedIn Pinterest WhatsApp Email

Alzheimer’s quietly ravages the brain long before symptoms appear and now scientists have new clues about the dominolike sequence of those changes — a potential window to one day intervene.

A large study in China tracked middle-aged and older adults for 20 years, using regular brain scans, spinal taps and other tests.

Compared to those who remained cognitively healthy, people who eventually developed the mind-robbing disease had higher levels of an Alzheimer’s-linked protein in their spinal fluid 18 years prior to diagnosis, researchers reported Wednesday. Then every few years afterward, the study detected another so-called biomarker of brewing trouble.

Scientists don’t know exactly how Alzheimer’s forms. One early hallmark is that sticky protein called beta-amyloid, which over time builds up into brain-clogging plaques. Amyloid alone isn’t enough to damage memory — plenty of healthy people’s brains harbor a lot of plaque. An abnormal tau protein that forms neuron-killing tangles is one of several co-conspirators.

The new research, published in the New England Journal of Medicine, offers a timeline for how those abnormalities pile up.

The study’s importance “cannot be overstated,” said Dr. Richard Mayeux, an Alzheimer’s specialist at Columbia University who wasn’t involved in the research.

“Knowledge of the timing of these physiological events is critical” for testing new ways of treating and maybe eventually even preventing Alzheimer’s, he wrote in an accompanying editorial.

The findings have no practical implications yet.

More than 6 million Americans, and millions more worldwide, have Alzheimer’s, the most common form of dementia. There’s no cure. But last year a drug named Leqembi became the first approved with clear evidence that it could slow the worsening of early Alzheimer’s — albeit for a few months.

It works by clearing away some of that gunky amyloid protein. The approach also is being tested to see if it’s possible to delay Alzheimer’s onset if high-risk people are treated before symptoms appear. Still other drugs are being developed to target tau.

Tracking silent brain changes is key for such research. Scientists already knew that in rare, inherited forms of Alzheimer’s that strike younger people, a toxic form of amyloid starts accumulating about two decades ahead of symptoms and at some point later tau kicks in.

The new findings show the order in which such biomarker changes occurred with more common old-age Alzheimer’s.

Researchers with Beijing’s Innovation Center for Neurological Disorders compared 648 people eventually diagnosed with Alzheimer’s and an equal number who remained healthy. The amyloid finding in future Alzheimer’s patients was the first, 18 years or 14 years prior to diagnosis depending on the test used.

Differences in tau were detected next, followed by a marker of trouble in how neurons communicate. A few years after that, differences in brain shrinkage and cognitive test scores between the two groups became apparent, the study found.

“The more we know about viable Alzheimer’s treatment targets and when to address them, the better and faster we will be able to develop new therapies and preventions,” said Claire Sexton, the Alzheimer’s Association’s senior director of scientific programs. She noted that blood tests are coming soon that promise to also help by making it easier to track amyloid and tau.

Share. Facebook Twitter Pinterest LinkedIn Reddit WhatsApp Telegram Email
Previous ArticleFDA warns against smartwatches that claim to measure blood sugar without needles
Next Article Black-owned grocery store in west suburbs opens doors to Black entrepreneurs
Staff
  • Website

Related Posts

Unbreakable: Black Women and Mental Health

A Question of a Government Shutdown?

Democrats Dig In: Healthcare at the Center of Looming Shutdown Fight

Leave A Reply Cancel Reply

Video of the Week
https://www.youtube.com/watch?v=AxFXtgzTu4U
Advertisement
Video of the Week
https://www.youtube.com/watch?v=OjfvYnUXHuI
ABOUT US

 

The Windy City Word is a weekly newspaper that projects a positive image of the community it serves. It reflects life on the Greater West Side as seen by the people who live and work here.

OUR PICKS

2025 Subaru Forester: Walkaround & Features!

What’s Funny? Lil Rel Howery and Knowledge Beckom’s new festival should have the answer

2 Minute Warning – 2025 Invesco QQQ Orange Blossom Classic: Built on History, Fueled by Pride

MOST POPULAR

Unbreakable: Black Women and Mental Health

A Question of a Government Shutdown?

Democrats Dig In: Healthcare at the Center of Looming Shutdown Fight

© 2025 The Windy City Word. Site Designed by No Regret Medai.
  • Home
  • Lifestyle
  • Podcast
  • Contact Us

Type above and press Enter to search. Press Esc to cancel.