Abreu played all 60 games in the pandemic-shortened season in 2020, helping the Sox to their first playoff appearance since 2008. He slashed .317/.370/.617 with 15 doubles, 19 home runs, 60 RBIs, 148 total bases and 34 extra-base hits. He led the AL in hits, RBIs, slugging percentage, total bases and extra-base hits.